[Adta] RE: Susan Kleinman
Jody Cassell
movingtolearn at nc.rr.com
Mon Feb 12 19:14:42 EST 2007
How wonderful that you are getting the word out in Glamour! Yeah, Susan!
Jody Cassell
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Sent: Monday, February 12, 2007 5:16 PM
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Subject: Adta Digest, Vol 16, Issue 35
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Today's Topics:
1. Re: Fw: COMMON GENE VERSION OPTIMIZES THINKING -- BUT WITH A
POSSIBLE DOWNSIDE (Cynthia BERROL)
2. RE: Glamour, FYI (skdmt2)
3. Fw: CALL-IN TOMORROW Support SCHIP - Call Congress Tomorrow,
Feb 13! (Dianne Dulicai)
----------------------------------------------------------------------
Message: 1
Date: Mon, 12 Feb 2007 12:00:32 -0800 (PST)
From: Cynthia BERROL <cberrol at sbcglobal.net>
Subject: Re: [Adta] Fw: COMMON GENE VERSION OPTIMIZES THINKING -- BUT
WITH A POSSIBLE DOWNSIDE
To: Barbara A Busse <busse002 at mc.duke.edu>, adta at adta.org
Message-ID: <952943.98212.qm at web80803.mail.mud.yahoo.com>
Content-Type: text/plain; charset=iso-8859-1
Barbara,
As always, somevery interesting information here,
Thank you,
Cynthia
--- Barbara A Busse <busse002 at mc.duke.edu> wrote:
>
> Thought this was very interesting. Barbara Busse
> ----- Forwarded by Barbara A Busse/MCLibrary/mc/Duke
> on 02/12/2007 10:45 AM
> -----
>
>
> "NIH OLIB
>
> (NIH/OD)"
>
> <olib at OD.NIH.GOV>
> To
> Sent by: NIH news
> NIHPRESS at LIST.NIH.GOV
> releases and news
> cc
> items
>
> <NIHPRESS at LIST.NI
> Subject
> H.GOV> COMMON GENE
> VERSION OPTIMIZES
> THINKING --
> BUT WITH A POSSIBLE
> DOWNSIDE
>
> 02/09/2007 09:24
>
> AM
>
>
>
>
>
> Please respond to
>
> "NIH OLIB
>
> (NIH/OD)"
>
> <olib at OD.NIH.GOV>
>
>
>
>
>
>
>
>
>
> U.S. Department of Health and Human Services
> NATIONAL INSTITUTES OF HEALTH
> NIH News
> National Institute of Mental Health (NIMH)
> <http://www.nimh.nih.gov/>
>
> EMBARGOED FOR RELEASE: Thursday, February 8, 2007,
> 5:00 p.m. ET
>
> CONTACT: Jules Asher, NIMH press office,
> 301-443-4356, <e-mail:
> NIMHpress at nih.gov>
>
> COMMON GENE VERSION OPTIMIZES THINKING -- BUT WITH A
> POSSIBLE DOWNSIDE
>
> Most people inherit a version of a gene that
> optimizes their brain's
> thinking circuitry, yet also appears to increase
> risk for schizophrenia*, a
> severe mental illness marked by impaired thinking,
> scientists at the
> National Institutes of Health's (NIH) National
> Institute of Mental Health
> (NIMH) have discovered. The seeming paradox emerged
> from the first study
> to explore the effects of variation in the human
> gene for a brain master
> switch, DARPP-32.
>
> The researchers identified a common version of the
> gene and showed how it
> impacts the way two key brain regions exchange
> information, affecting a
> range of functions from general intelligence to
> attention.
>
> Three fourths of subjects studied had at least one
> copy of the version that
> results in more efficient filtering of information
> processed by the brain's
> executive hub, the prefrontal cortex. However, the
> same version was also
> more prevalent among people who developed
> schizophrenia, a severe mental
> illness marked by delusions, hallucinations and
> impaired emotion that
> affects one percent of the population.
>
> "We have found that DARPP-32 shapes and controls a
> circuit coursing between
> the human striatum and prefrontal cortex that
> affects key brain functions
> implicated in schizophrenia, such as motivation,
> working memory and reward
> related learning," explained Andreas
> Meyer-Lindenberg, M.D.
>
> "Our results raise the question of whether a gene
> variant favored by
> evolution, that would normally confer advantage, may
> translate into a
> disadvantage if the prefrontal cortex is impaired,
> as in schizophrenia,"
> added Daniel Weinberger, M.D. "Normally, enhanced
> cortex connectivity with
> the striatum would provide increased flexibility,
> working memory capacity
> and executive control. But if other genes and
> environmental events conspire
> to render the cortex incapable of handling such
> information, it could
> backfire -- resulting in the neural equivalent of a
> superhighway to a
> dead-end."
>
> Meyer-Lindenberg, Weinberger and colleagues in the
> NIMH Genes, Cognition
> and Psychosis program report their results in the
> February 9, 2007 issue of
> the "Journal of Clinical Investigation".
>
> Previous studies in animals over two decades, most
> notably by Nobel
> Laureate and NIMH grantee Paul Greengard, M.D.,
> Rockefeller University, had
> established that DARPP-32 in the striatum switches
> streams of information
> from multiple brain chemical systems for processing
> by the cortex. Both the
> neurotransmitter that it works through, dopamine,
> and the chromosomal site
> of its gene have been implicated in schizophrenia.
>
> "Although several groups have looked for possible
> clinical relevance of
> DARPP-32, they have not met with great success,"
> noted Greengard. "This
> study shows a strong connection between this
> molecule and human cognition
> -- and perhaps with schizophrenia."
>
> "These first glimpses of DARPP-32 at work in the
> living human brain build
> on a quarter century of investigations by
> Greengard's team that ultimately
> linked this pivotal protein to depression and
> substance abuse as well as to
> schizophrenia," added NIMH Director Thomas Insel,
> M.D.
>
> To understand DARPP-32's role in the human brain,
> the NIMH researchers used
> genetic, structural and functional magnetic
> resonance imaging, and
> post-mortem techniques to identify the human gene's
> variants and their
> functional consequences. Seventy five percent of
> subjects had the most
> common version of the gene, which boosted circuit
> activation, structural
> and functional connectivity and performance on
> thinking tasks, likely by
> increasing gene expression. In 257 affected
> families, people with
> schizophrenia were more likely to have this common
> version of the DARPP-32
> gene.
>
> Also participating in the study were: Richard
> Straub, Barbara Lipska, Beth
> Verschinski, Terry Goldberg, Joseph Callicott,
> Michael Egan, Stephen
> Huffaker, Venkata Mattay, Bhaskar Kolachana, Joel
> Kleinman, NIMH.
>
> The National Institute of Mental Health (NIMH)
> mission is to reduce the
> burden of mental and behavioral disorders through
> research on mind, brain,
> and behavior. More information is available at the
> NIMH website <
> http://www.nimh.nih.gov>.
>
> The National Institutes of Health (NIH) -- The
> Nation's Medical Research
> Agency -- includes 27 Institutes and Centers and is
> a component of the U.S.
> Department of Health and Human Services. It is the
> primary federal agency
>
=== message truncated ===
------------------------------
Message: 2
Date: Mon, 12 Feb 2007 15:32:46 -0500
From: "skdmt2" <skdmt2 at bellsouth.net>
Subject: [Adta] RE: Glamour, FYI
To: "'adta list serve'" <adta at adta.org>
Message-ID:
<20070212203232.IDEL1815.ibm63aec.bellsouth.net at activevmmhybc5>
Content-Type: text/plain; charset="us-ascii"
FYI - March issue, Glamour- article, entitled " How to Stop Punishing and
Start Respecting your Body"
starts on page 306
Although d/mt is not mentioned, I am mentioned as a dance therapist, as well
as a couple of body image "tips" I provided
( kind of)- they rewrote them a bit. Still good PR for us.
Susan Kleinman, MA, ADTR NCC
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Message: 3
Date: Mon, 12 Feb 2007 16:56:53 -0500
From: "Dianne Dulicai" <dianne.dulicai at cox.net>
Subject: [Adta] Fw: CALL-IN TOMORROW Support SCHIP - Call Congress
Tomorrow, Feb 13!
To: "adta" <adta at adta.org>
Message-ID: <000a01c74ef0$b4bbe9c0$6601a8c0 at Dianne>
Content-Type: text/plain; charset="iso-8859-1"
----- Original Message -----
From: MYRNA Mandlawitz
To: Valerie Williams ; Todd Haiken ; Tim Nanof ; Ted Kozlik ; Ted Feinberg ;
Susan Karr ; Stan Truman ; Stacy Skalski ; Scott Barstow ; Sandra Schefkind
; Ron Palomares ; Robyne Davis ; Rebecca Milliken ; Paula Howie ; Patti
Ralabate ; Neil Snyder ; Nancy Reder ; Nancy McFall Jean ; Melanie McCoy ;
Mary Louise Embry ; Mary Beth Klotz ; Lisa Thomas ; Libby Nealis ; Leslie
Lewis-Jackson ; Lee Johnson ; Krista Heckler ; Kim Krocker ; Kathryn Coleman
; Karen Ferguson ; Judy Simpson ; jsmulson ; Jayme Murray ; Isadora Hare ;
Ikeita Cantu-Hinojosa ; Ellie Ehrlich ; Ellen Yacoe ; Ellen Fern ; Don
Cutcher ; Dianne Dulicai ; Deborah Ziegler ; David Hawkins ; Dave Mason ;
Daniel Blair ; Chris Campbell ; Cathy Malchiodi ; Beth Nichols-Howarth ;
Annie Toro ; Amy Garcia ; Alvin Crawley ; christine hazelett
Sent: Monday, February 12, 2007 3:59 PM
Subject: FYI: CALL-IN TOMORROW Support SCHIP - Call Congress Tomorrow, Feb
13!
Am sure some of you have this, but just in case...
MM
----- Original Message -----
From: Coalition on Human Needs
To: mandlawitz at verizon.net
Sent: Monday, February 12, 2007 2:36 PM
Subject: Support SCHIP - Call Congress Tomorrow, Feb 13!
SUPPORT SCHIP - CALL CONGRESS TOLL-FREE ON FEB. 13th!
>From our friends at Families USA
Currently, there are over 9 million uninsured children in this country.
Nearly three quarters of them are eligible for the State Children's Health
Insurance Program (SCHIP) or Medicaid today, but they aren't enrolled in
either program. Unless Congress is willing to let the SCHIP program die this
year, it must reauthorize it. Tomorrow, February 13 call your Members of
Congress and remind them of the importance of this vital program.
TAKE ACTION
Call Congress, toll-free at 1-877-509-KIDS, and
Tell them:
a.. Today, SCHIP provides high quality, comprehensive, affordable health
coverage to more than 4 million children who would otherwise be uninsured.
These children get access to vital health care services they would not
otherwise be able to afford.
b.. Congress must ensure that there is enough money to at least get the
children who are already eligible for Medicaid or SCHIP enrolled. To do
this, states will need approximately $50-$60 billion in new federal funds
over the next five years.
c.. No child should lose health coverage because of a shortage of federal
funds. The $50-60 billion includes funding to ensure that no child who is
enrolled in SCHIP today--and who continues to be eligible--will lose
coverage because of a shortfall in federal funds.
d.. For more information, check out the Medicaid and SCHIP Action Center.
Thanks for doing your part to guarantee high-quality, affordable health care
for all children!
=======================
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